Borderer Darcy Graham was among the try-scorers as the white-shirted Scots, captained by fellow ex-Hawick player Stuart Hogg, claimed their tenth victory in a row against their blue-clad visitors at Edinburgh’s Murrayfield Stadium, running up a record score in the process.
Here’s how it went in pictures ...
9. Scotland v Italy
Huw Jones of Scotland breaks the tackle of Edoardo Padovani of Italy during the Guinness Six Nations match between Scotland and Italy at Murrayfield on March 20, 2021 in Edinburgh (Photo by Stu Forster/Getty Images) Photo: Stu Forster
10. Scotland v Italy
Stuart Hogg congratulates team-mate Duhan van der Merwe of Scotland after scoring their side's eighth try during the Guinness Six Nations match between Scotland and Italy at Murrayfield on March 20, 2021 in Edinburgh (Photo by Stu Forster/Getty Images) Photo: Stu Forster
11. Scotland v Italy
Scotland flanker Hamish Watson gets tackled during the Six Nations international rugby union match between Scotland and Italy at Murrayfield Stadium in Edinburgh on March 20, 2021 (Photo by Andy Buchanan/AFP via Getty Images) Photo: ANDY BUCHANAN
12. Scotland v Italy
Gregor Townsend, head coach of Scotland, looks on prior to the Guinness Six Nations match between Scotland and Italy at Murrayfield on March 20, 2021, in Edinburgh (Photo by Stu Forster/Getty Images) Photo: Stu Forster