To date, the Scots and Irish are evens, each having won 66 of the 137 games they’ve played since 1877, with five drawn, but Gregor Townsend will be hoping to tip that balance back in favour of the Dark Blues after losing the last five of those matches on the trot.
The Irish have had the upper hand in recent years, having won all but six of the 27 times the two teams have met this century and not lost for four years.
Scotland’s six 21st century wins were in September 2001, August 2007, March 2010, August 2011, February 2013 and February 2017.
Ahead of Scotland and Ireland’s round-four game, kicking off at 3pm and being broadcast live by BBC One, here we take a look back at the Scots’ last dozen games against the Irish ...
1. Scotland's last 12 rugby matches against Ireland
Ireland 31, Scotland 16: December 5, 2020, Autumn Nations Cup
Scotland captain Stuart Hogg looking to chip a ball past Hugo Keenan at Dublin's Aviva Stadium. (Photo by Brian Lawless/pool/Getty Images) Photo: Pool
2. Scotland's last 12 rugby matches against Ireland
Ireland 19, Scotland 12: February 1, 2020, Six Nations
Scotland's Stuart Hogg fumbling the ball and dropping it to miss out on a try at the Aviva Stadium in Dublin (Photo by Paul Faith/AFP via Getty Images) Photo: PAUL FAITH
3. Scotland's last 12 rugby matches against Ireland
Ireland 27, Scotland 3: September 22, 2019, Rugby World Cup
Scotland's Darcy Graham running with the ball at the International Stadium Yokohama in Japan (Photo by Charly Triballeau/AFP via Getty Images) Photo: CHARLY TRIBALLEAU
4. Scotland's last 12 rugby matches against Ireland
Scotland 13, Ireland 22: February 9, 2019, Six Nations
Scotland's Finn Russell makes a break to set up a try at Murrayfield in Edinburgh (Photo by Stu Forster/Getty Images) Photo: Stu Forster