Forty-five-year-old Darren Richardson, from Galashiels, and 24-year-old John McMillan, of no fixed abode, are charged with assault to severe injury, permanent disfigurement, impairment and attempted murder.
They also face a charge of behaving in a threatening or abusive manner.
It follows an incident at a house in Hawthorn Road, Galashiels, last Wednesday night.
Both men made no plea and the case was continued for further examination. They were both remanded in custody and due to appear in court again next week