The A7 at Galashiels Road in Stow is closed in both directions at the B6362 Townfoot junction, following an accident involving a car and a motorcycle.
A spokesman for Police Scotland said: “Police in the Borders are attending a serious road traffic collision near Galashiels involving a motorcycle and a car.
“The incident occurred on the A7, around four miles north of the town at around 8am this morning (Tuesday, February 17).
“A 50-year-old man suffered serious injuries and is currently being cared for by the Scottish Ambulance Service.
“The road has been closed in both directions and diversions are in place.
“Police are continuing with their enquiries.”
Check back on this story for updates.