Diversions are in place on the A68 following a serious accident between the Ravenswood roundabout and Earlston.
Police were called to the accident, half a mile north of the Ravenswood roundabout, at around 4.15pm.
A Police Scotland spokesperson said: “Two vehicles were involved in the road traffic collision.
“The Scottish Ambulance Service is in attendance.”
Drivers are being warned to expect delays.